A sparse inherited condition named Darier\'s disease (DAR), which was initially identified by a famous French dermatologist, Jean Darier, is caused by the defect in the mutation of the ATPA2 gene. Darier\'s disease is mainly represented by crusty dark patches over the skin, rarely with exudates, and it is otherwise termed as Darier\'s white patches, keratosis follicularis, keratotic papules, or dyskeratotic follicularis. It is an autosomal disorder, and it is tested by genetic testing registry, skin biopsy, and by means of obtaining a familial history. Around 90% of the cases are treated by oral retinoids and topical application. Remaining cases need a surgical repair. The person affected with this disease may have chances of getting mood disorders.