Background: Nursing staff are particularly vulnerable to aggression because they are frequently on the front lines: physical assault at work was reported by 46% of nurses working in working-age psychiatric services and 64% of nurses working in older people's psychiatric services, respectively. Nursing and Midwifery Council (NMC), 2001, p. 104, this study is based on video-assisted teaching is an awareness program about de-escalation and breakaway technique knowledge and attitude should be improved among staff nurse. Aims and objectives: To assess the level of knowledge and attitude regarding de-escalation and breakaway technique among staff nurses, to assess the effectiveness of video-assisted teaching on knowledge and attitude, and to associate the level of knowledge and attitude regarding de-escalation and breakaway technique among staff nurses in the experimental and control groups with their selected demographic variables. Materials and methods: The study employed a quasi-experimental, non-randomized control group design. A convenience sampling technique was used to select a sample of 200 staff nurses. A structured closed-ended questionnaire and the management of aggression and violence attitude scale (MAVAS) were used to assess it. Results: The study found that video-assisted teaching had a statistically significant impact on staff nurses’ knowledge and attitudes about de-escalation and breakaway techniques for aggressive behavior at the p value 0.001 level. Conclusion: According to the findings, video-assisted teaching was effective in improving staff nurses’ knowledge and attitudes about de-escalation and breakaway techniques for aggressive behavior.