Pondicherry Journal of Nursing

Register      Login

VOLUME 16 , ISSUE 1 ( January-March, 2023 ) > List of Articles


Effectiveness of Self-care Measures on Side Effects of Chemotherapy, Performance Status, and Quality of Life among Patients Undergoing Chemotherapy at Selected Hospitals at Puducherry

Vijayanandh Mani, Renuka Kandaswamy

Keywords : Cancer, Chemotherapy, Quality of life, Self-care

Citation Information : Mani V, Kandaswamy R. Effectiveness of Self-care Measures on Side Effects of Chemotherapy, Performance Status, and Quality of Life among Patients Undergoing Chemotherapy at Selected Hospitals at Puducherry. 2023; 16 (1):3-9.

DOI: 10.5005/jp-journals-10084-13153

License: CC BY-NC 4.0

Published Online: 19-05-2023

Copyright Statement:  Copyright © 2023; The Author(s).


Background: Cells that are uncontrolled in their growth, division, and invasion into other tissues are called cancerous tumors. Cell division is controlled by a person without cancer. In the majority of tissues, healthy cells reproduce and divide in a controlled manner to produce new healthy cells. This regular cell division becomes uncontrolled in cancer. Because of gene mutations, cells undergo morphological changes. All cancerous cells are the offspring of cancerous cells. Malignant cells are also blamed for the development of cancer cells within our bodies. During treatment for cancer, self-care is a crucial and necessary component of pleasure and wellness. According to research, self-care routines help lessen the negative consequences of stress, poor sleep, and anxiety. Objectives: The aim is to evaluate the effectiveness of self-care measures on side effects of chemotherapy, performance status, and quality of life among patients undergoing chemotherapy in selected hospital at Puducherry. Methodology: The quantitative approach and Quasi experimental one group pre-test—post-test research design was used in this study among cancer patients at selected hospitals. Purposive sampling technique was adapted and sample size was 30. Samples were interviewed through standardized observation checklist to assess the self-care measures, side effects of chemotherapy, performance status, and quality of life. Results: The effectiveness of self-care instruction module among cancer patients undergoing chemotherapy in pretest 20 (66.7%) has poor quality of life, and 10 (33.3%) have neutral quality of life after giving self-care instruction module, 30 (100) have neutral quality of life. Cancer patients undergoing chemotherapy in Eastern cooperative oncology group (ECOG) performance status scale as in pretest 23 (76.7%) were in symptomatic, but ambulatory and symptomatic (<50%) in bed were 7 (23.3%) after giving self-care instruction module; 13 (43.3%) were in asymptomatic; and 17 (56.7%) were symptomatic but ambulatory. The overall symptoms of chemotherapy in pretest 19 (63.3%) have moderate symptoms and 11 (36.7%) have mild symptoms after giving self-care instruction module. Two (6.7%) have moderate symptoms, and 28 (93.3%) have mild symptoms. Conclusion: The study revealed that the self-care measures on side effects of chemotherapy, performance status, and quality of life among cancer patients who are undergoing chemotherapy were effective, and they changed the quality of life of cancer patients.

PDF Share
  1. World Health Organization. September 12, 2018, Accessed on: 19 December 2018.
  2. National Cancer Institute. September 17, 2007, Accessed on: 28 March 2018.
  3. Bray F, Møller B. Predicting the future burden of cancer. Nat Rev Cancer 2006;6(1):63–74. DOI: 10.1038/nrc1781.
  4. Jivarajani PJ, Patel HV, Mecwan RR, Solanki JB, Pandya VB. Major sites of cancer occurrence among men and women in Gandhinagar district, India. Indian J Community Med. 2015;40(1):56–61. DOI: 10.4103/0970-0218.149273.
  5. Saranath D, Khanna A. Current status of cancer burden: Global and Indian scenario. Biomed Res J 2014;1(1):1–5. DOI: 10.4103/2349-3666.240996.
  6. Raffaghello L, Lee C, Safdie FM, Wei M, Madia F, Bianchi G, et al. Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy. Proc Natl Acad Sci USA 2008;105(24):8215–8220. DOI: 10.1073/pnas.0708100105.
  7. Conklin KA. Chemotherapy-associated oxidative stress: Impact on chemotherapeutic effectiveness. Integr Cancer Ther 2004;3(4): 294–300. DOI: 10.1177/1534735404270335.
  8. Lee C, Longo VD. Fasting vs dietary restriction in cellular protection and cancer treatment: from model organisms to patients. Oncogene 2011;30(30):3305–3316. DOI: 10.1038/onc.2011.91.
  9. Chabner BA, Roberts TG Jr. Timeline: Chemotherapy and the war on cancer. Nat Rev Cancer 2005;5(1):65–72. DOI: 10.1038/nrc1529.
  10. Liu B, Ezeogu L, Zellmer L, Yu B, Xu N, Joshua Liao D. Protecting the normal in order to better kill the cancer. Cancer Med 2015;4(9): 1394–1403. DOI: 10.1002/cam4.488.
  11. Carelle N, Piotto E, Bellanger A, Germanaud J, Thuillier A, Khayat D. Changing patient perceptions of the side effects of cancer chemotherapy. Cancer 2002;95(1):155–163. DOI: 10.1002/cncr.10630.
  12. Coates A, Abraham S, Kaye SB, Sowerbutts T, Frewin C, Fox RM, et al. On the receiving end-patient perception of the side-effects of cancer chemotherapy. Eur J Cancer Clin Oncol 1983;19(2):203–208. DOI: 10.1016/0277-5379(83)90418-2.
  13. Broeckel JA, Jacobsen PB, Horton J, Balducci L, Lyman GH. Characteristics and correlates of fatigue after adjuvant chemotherapy for breast cancer. J Clin Oncol 1998;16(5):1689–1696. DOI: 10.1200/jco.1998.16.5.1689.
  14. Berger AM. Patterns of fatigue and activity and rest during adjuvant breast cancer chemotherapy. Oncol Nurs Forum 1998;25(1):51–62. PMID: 9460773.
  15. Sitzia J, Huggins L. Side effects of cyclophosphamide, methotrexate, and 5-fluorouracil (CMF) chemotherapy for breast cancer. Cancer Pract 1998;6(1):13–21. DOI: 10.1046/j.1523-5394.1998.1998006013.x.
  16. Jacobsen PB, Hann DM, Azzarello LM, Horton J, Balducci L, Lyman GH. Fatigue in women receiving adjuvant chemotherapy for breast cancer: characteristics, course, and correlates. J Pain Symptom Manage 1999;18(4):233–242. DOI: 10.1016/s0885-3924(99)00082-2.
  17. Bower JE, Ganz PA, Desmond KA, Rowland JH, Meyerowitz BE, Belin TR. Fatigue in breast cancer survivors: Occurrence, correlates, and impact on quality of life. J Clin Oncol 2000;18(4):743–753. DOI: 10.1200/jco.2000.18.4.743.
  18. Jacobsen PB, Stein K. Is fatigue a long-term side effect of breast cancer treatment? Cancer Control 1999;6(3):256–63. DOI: 10.1177/107327489900600304.
  19. Goodman M. Managing the side effects of chemotherapy. Semin Oncol Nurs 1989;5(2 Suppl 1):29–52. DOI: 10.1016/0749-2081 (89)90080-6.
  20. Foster C, Brown J, Killen M, Brearley S. The NCRI cancer experiences collaborative: defining self-management. Eur J Oncol Nurs 2007;11(4): 295–297. DOI: 10.1016/j.ejon.2007.08.002.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.