Background: Due to the lockdown, the coronavirus disease 2019 (COVID-19) pandemic may cause changes to daily life. Children may be exposed to the childhood obesity epidemic caused by COVID-19. The study aimed to assess lifestyle behavior among obese children during the second wave of the COVID-19 lockdown. Materials and Methods: Descriptive research was undertaken among obese children in Puducherry. Purposive sampling was used to select a 150-person sample size. Both the quantitative technique and the descriptive design were used. Data were collected by using a semi-structured questionnaire related to demographic and lifestyle behavior. Results: A total of 150 participants were eligible. The finding reveals that out of 150 (100%) samples, 94 (62.67%) had an average lifestyle, 48 (32%) had an unhealthy lifestyle, and 8 (5.33%) had a healthy lifestyle among obese children during the second wave of the COVID-19 lockdown. The demographic variable “number of children in the family” (χ² = 11.107, p = 0.025) had a statistically significant association with the lifestyle behavior of obese children during the second wave of the COVID-19 lockdown (p < 0.05). The other demographic variables had no statistically significant association with lifestyle behavior among obese children during the second wave of the COVID-19 lockdown. Conclusion: obese youngsters often led typical lifestyles. Therefore, during the second wave of the COVID-19 lockdown, nursing education should have a greater emphasis on the lifestyle choices of obese children.