Pregnancy is a period of immense joy and excitement. High-risk pregnancy is one that is complicated by factor or factors that adversely affect the pregnancy outcome, maternal or prenatal or both. Hospitalization leads to stress and that may lead to decreased coping ability of the mother. Relaxation techniques are a powerful tool for coping with stress and promoting long-term health in mothers with high-risk pregnancy by slowing down the body and quietening the mind. To evaluate the effectiveness of Benson's relaxation therapy on stress and coping mechanism among high-risk antenatal women. Preexperimental design was used for the study. The population for the study was 30 high-risk antenatal women selected by using the nonprobability purposive sampling technique and setting was the antenatal ward. Pretest was done by using the structured questionnaire and the perceived stress scale and coping scale. Posttest was conducted after administration of Benson's relaxation therapy. The result shown that the level of stress and coping among high risk antenatal women in pretest mean value of stress was 3.27 and the posttest mean value of stress was 7.27. The obtained Wilcoxon value of stress was 4.829 and the pretest mean value of coping was 25.1 and posttest mean value of coping was 16.63 and the obtained paired t-test value of coping was 19.298. It was statistically significant at p < 0.001. Therefore, the Benson's relaxation therapy was more effective. Thus, the study concludes that Benson's relaxation therapy was found to be effective to reduce the stress and coping among high-risk antenatal women.